Saturday, February 18, 2012

Template – Bleeding PR


HISTORY
·         Age
o   Crohn’s disease – 2 peaks (20-40, >70)
·         Gender
·         Presenting complaint
o   Bleeding PR
·         History of presenting complaint
o   Previously well
o   Color –
§  black/tarry – upper GI bleeding
§  red wine – proximal large bowel
§  bright red – anal, low rectum
o   Amount of bleeding
o   association with defecation
§  mixed with feces à higher than sigmoid colon
§  on surface of feces à lower sigmoid colon, rectum, anal canal
§  following defecation à haemorrhoids
§  blood passed by itself à rapidly bleeding Ca, IBD, diverticulosis, severe upper GI bleeding
§  blood on toilet paper – haemorrhoids, anal fissures
o   Mucus
o   Pain during defecation à fissure, anal Ca, rectal Ca obstructing the lumen
o   Tenesmus – intense, painful, fruitless effort to defecation à space occupying lesion in the rectum
o   Previous bowel habits
§  Constipation
§  Frequent diarrhoea
§  Consistency of stools
§  Incontinence and soiling
o   Abdominal pain
o   DD
§  Haemorrhoids – pruritis, lump coming out
§  Colo-rectal Ca –
·         Cecal tumor à RIF pain 
·         Mucus à mucus producing adenoma
·         Caecal tumor à RIF pain
·         Ca rectum à
o   increased frequency with scanty amount
o   PR bleeding
o   Tenesmus
·         Ca at amula of rectum à early morning bloody diarrhoea
§  Fissure in ano
§  IBD – mucus, joint problems, conjunctivitis
§  Solitary rectal ulcer
§  TB – cough, fever, night sweats
§  Bleeding disorders
§  Angiodysplasia
§  Bleeding disorders
§  Diverticular disease
o   Aetiology
o   Complications
§  Obstruction à constipation, abdominal distension, vomiting, abdominal pain
§  Anaemia à Faintishness, lethargy
§  Spread
·         Local à
o    recurrent UTI
o   Vaginal discharge in females
o   Back pain radiating along the thigh (sacral plexus)
o   Faecouria, pneumaturia, haematuria à bladder
o   Haematospermia à
o   Fistula
o   Lymphadenoma
·         Metastases
o   Liver à history of jaundice, RHP, LOW, LOA
o   Lungs à chest pain, SOB, persistent dry cough, wheezing, haemoptesis
o   Adrenals
o   Brain à headache, visual disturbances, early morning vomiting, drowsiness, fits
o   Bone
o   Fitness for surgery and anaesthsia
§  Exertional dyspnoea, chest pain, orthopnoea, PND
§  Urinay habits
§  Lower limb joint problems
·         Positioning for APR
·         NSAIDS
·         IBD – extraintestinal manifestations
o   PMH
o   PSH
§  Colonic polyps, Ca, Haemorrhoeids, colonoscopy and biopsy
§  Cholecystectomy à increased risk
§  Uretero-sygmoidostomy à increased risk of stump Ca
o   Drug history à aspirin, heparin, warfarin
o   Allergies à foods, drugs and plasters
o   Family history
§  Polyposis coli
§  Bowel Ca
§  Breast Ca
§  Ovarian Ca
§  DM
§  HT
§  Prostate Ca
o   Dietary Histtory
·         High fat
·         Low fibre
o   Social history
§  Level of education
§  Details of the family
§  Income
§  Family support
§  Smoking
§  Alcohol
§  Toilet - ? public
§  Nearest hospital
§  Transport
§  Consent for colonostomy and surgery
EXAMINATION
General
·         BMI
·         Ill/well looking
·         Pale
·         Jaundice
·         Conjunctivitis, joint swelling (IBD)
·         Features of nutritional deficiencies
·         Supraclavicular lymph node
·         Ankle edema
Abdominal Examination
·         Sister Mary Joseph’s node
PR Examination
·         Anal scars
·         Perineal tears in females
·         Skin tags
·         Skin excoriation
·         Prolapsed haemorrhoids
·         Genital and perianal warts
·         External opening og sinus/fistula
·         Sphincter tone/soiling
·         Sever pain à anal fissure, abandon the procedure
·         Anal canal à mass, polyp, ulcers,
·         If growth à
o   distant from anal verge
o   upper margin
o   contact bleeding
o   fixed to sacrum
o   circumference
o   consistency
o   tenderness
·         prostate
·         VE – masses in the pouch of Douglus
Anoscopy/proctoscopy
·         Haemorrhoids à position
·         State of mucosa
·         Anal polyps
·         Anal growths
Biopsy
·         Yeoman’s Forceps
INVESTIGATIONS
For Diagnosis
·         Rigid sigmoidoscopy (25-30 cm)
o   Visualizes the anal canal and the rectum
o   Bowel preparation à Micro-enema
·         Flexible sygmoidoscopy (70 cm)
o   Up to splenic flexure
·         Colonoscopy and biopsy
o   Preparation
§  Informed consent
§  Low fibre diet for 3 days
§  Liquid diet on the day
§  Polyethylene glycol (klean prep) 4 packets in 4 liters
·         1 L in 1 hr à 1 L clear water for 1 hr à ………………..
§  IV cannulae
§  Iv midazolam 2-3 mg à microenema in morning Hiscosin bromide
·         Double contrast Ba enema
o   Determines the level of obstruction
o   Ca of colon
o   Ulcerative colitis
o   Diverticular disease of the colon
o   Familial adenomatous polyposis
o   Assessment of anastomotic leak
For Staging
·         USS abdomen
o   Liver 2ries
o   Lymph node enlargement
o   Ascites
·         Transrectal ultrasonography
·         CXR
o   Lung mets
o   Pleural effusion
o   Osteolytic lesions of the ribs
o   Mediastinal lymph nodes
·         CT abdomen
o   Better soft tissue enhancement
o   Liver mets, liver enlargement
o   Tumor
o   Level of invasion
·         Bone scan
·         CT Brain
To Assess Fitness for Anaesthesia
·         FBC with Hb
·         FBS
·         BU
·         SE
·         PT/INR
·         Serum proteins
·         ECG à echo, exercise ECG
·         CXR

MANAGEMENT
SEVERE PR BLEEDING
·         Assessment and resuscitation
o   ABC, IV fluids, blood transfusion
·         History, examination
·         Monitor à PR, RR, BP, input/output, CVP
·         UGIE
·         Colonoscopy
·         If colonoscopy cannot be done à angiography, radio-isotope scan (radio-labelled RBCs)
HAEMORRHOIDS
·         Exclude
o   Colorectal malignancy
o   IBD
o   Diverticular disease
o   Adenomatous polyposis à loose stools, lower abdominal pain, weight loss, blood and mucus diarrhoea
·         Stool softners
·         Bulking agents
·         Increased intake of fluids
·         1st degree à
o   Sclerotherapy
§  2-5 ml of 5% phenol in olive oil is injected above each haemorrhoids
§  If injected too superficial à mucosal sloughing (a white wheel)
§  If injected too deep à
·         Males – chemical prostatitis, impotence
·         Females – ano-vaginal fistula
§  Bradycardia
·         Leave the patient for sometime and ensure that PR is normal
·         No nausea, vomiting, light headedness à can go
§  Allergic reactions à anaphylaxis
·         2nd degree
o   Elastic band ligation
·         3rd and 4th degree
o   Hamorrhoidectomy
o   Stapled haemorrhoidoplexy
EXTERNAL PLEXUS HAEMATOMA
·         Perianal haematome
·         Maximum severity of pain – 2-3 days
·         May take up to 2 weeks to resolve
·         Tense dark blue swelling at the anal margin
·         Reassurance and analgesia
·         If large/ extremely painful à excision under LA
FISTULA IN ANO
·         Anal fistlectomy
ANAL FISSURE
·         Stool softners
·         Bulking agents
o    
§  Peutz-Jegher’s polyps
§  Juvenile polyp
o   Neoplastic
§  Adenomas à tubular, tubular villous, villous
§  Adeno Ca
§  Carcinoid tumor
CA COLON
·         Columnar cell adeno carcinoma
·         Clinical features
§  Left side
·         Stenoting variety
·         Features of intestinal obstruction
·         Pain – suprapubic coloc, constant ache (advanced)
·         Alteration of bowel habits – episodes of constipation followed by attacks of diarrhoea
·         Distension – relieved by passage of flatus
·         Palpable lump
·         Sigmoid – tenesmus, bladder symptoms
§  Right side
·         Anaemia – severe, unyielding to treatment
·         Mass in RIF
·         Intussusceptions – features of intermittent obstruction
·         Treatment
o   Remove the 1ry tumor and its draining locoregional lymph nodes
§  Right hemi-colectomy
§  Extended right hemicolectomy
§  If no obstruction à 1ry anastomosis
§  If obstruction à stoma
o   Inoperable tumors
§  Ascending colon – bypass using a iliocolic anastomosis
§  Upper part of the left colon – transverse colectomy
§  Pelvic colon – LIF colostomy
o   Adjuvant therapy
CA RECTUM
·         Clinical features
o   Can occur in youth
o   Adult presentation 55 years
o   Bleeding
§  Earliest and most common symptom
§  Stimulates haemorrhoids
o   Sense of incomplete defecation
§  Tenesmus
o   Alteration of the bowel habits
o   Ampulla of rectum à early morning bloody diarrhoea
o   Pain
§  Late symptom
§  Due to some degree of intestinal obstruction/local invasion
TREATMENT
·         Surgery
o   Sphincter saving AR
o   Removal of rectum with permanent colostomy APR
o   Endo-anal excision
o   =>3cm from the anal verge à APR
o   =>5 cm from anal verge à AR
o   =>2 cm from anal verge à ultra low AR
o   Fit enough to surgery + small tumor à curative surgery
o   Fit enough to surgery + metastasis à palliative surgery, colostomy
o   Fit enough to surgery + features of obstruction à defunctioning ileostomy/colostomy
o   Fit enough to surgery + extensive local spread à neo-adjuvant chemotherapy =/- small amount of radiotherapy à if done surgery should be done within 2 weeks à Downgrade the tumor (2-3 months) à surgery à chemoradiation (5-flouroucil + folinic acid
o    

1 comment:


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